Hybrid Closed-Loop Insulin Delivery Systems for People With Type 1 Diabetes

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Project Status:
Completed
Project Line:
Reference List
Project Sub Line:
Reference List
Project Number:
RA1260-000

Question

  1. What literature describes the potential clinical benefits and harms of commercially available hybrid closed-loop systems versus other insulin delivery methods in people of any age with type 1 diabetes?
  2. What literature describes the cost-effectiveness of commercially available hybrid closed-loop systems versus other insulin delivery methods in people of any age with type 1 diabetes?
  3. What are the evidence-based guidelines regarding the use of commercially available hybrid closed-loop systems in people of any age with type 1 diabetes?

Key Message

We found 4 health technology assessments, 2 systematic reviews, 39 randomized controlled trials, and 17 nonrandomized studies describing the clinical benefits and harms of commercially available hybrid closed-loop systems versus other insulin delivery methods in people of any age with type 1 diabetes. We found 6 economic evaluations describing the cost-effectiveness of commercially available hybrid closed-loop systems versus other insulin delivery methods in people of any age with type 1 diabetes. We found 2 evidence-based guidelines regarding the use of commercially available hybrid closed-loop systems in people of any age with type 1 diabetes.