Key Message
One systematic review and one randomized controlled trial were identified regarding the clinical effectiveness of hypodermoclysis in geriatric patients who are at risk of dehydration or who are dehydrated in long term care. No evidence was identified regarding the clinical effectiveness or cost-effectiveness of hypodermoclysis in frail patients who are at risk of dehydration or who are dehydrated in any setting. No evidence was identified regarding the cost-effectiveness of hypodermoclysis in geriatric patients who are at risk of dehydration or who are dehydrated in long term care. No evidence-based guidelines were identified regarding the use of hypodermoclysis in frail patients or patients in long term care.