Key Message
Two systematic reviews and one randomized controlled trial were identified regarding hypodermoclysis in patients who are frail or who are in long term care. Hypodermoclysis appeared to have fewer adverse effects or complications when compared with intravenous fluids but did not have a significantly better clinical improvement of dehydration. The studies were of low quality, with poor reporting of methods and small sample sizes. No economic evaluations were identified regarding hypodermoclysis in frail patients or patients in long term care, and no evidence-based guidelines were identified.