Internet-Delivered Cognitive Behavioural Therapy for Major Depressive Disorder and Anxiety Disorders: A Health Technology Assessment


Project Status:
Project Line:
Health Technology Review
Project Sub Line:
Optimal Use
Project Number:

Major depressive disorder (MDD) is the occurrence of one or more major depressive episodes that last at least two weeks. Anxiety disorders include a range of conditions, including generalized anxiety disorder, panic disorder, and social anxiety disorder. MDD and anxiety disorders may be treated with pharmacological and/or psychological interventions such as cognitive behavioural therapy (CBT). CBT delivered via the Internet (iCBT) may mitigate barriers to accessing face-to-face CBT such as geographical distance or cost of treatment.

CADTH, in collaboration with Ontario Health (Quality), completed an Optimal Use project on the use of iCBT in patients with mild to moderate MDD and anxiety. Ontario Health’s Quality business unit, formerly Health Quality Ontario, completed a systematic review of the clinical and economic evidence, as well as an economic analysis, and direct patient engagement for patient preferences and values. CADTH developed reviews for patient perspectives and experiences (literature review), and ethical and implementation issues related to iCBT.

Non-CADTH resources of interest to mental health professionals, patients and other stakeholders in mental health 

Toolkit for e-Mental Health Implementation

A resource for mental health professionals interested in implementing e-mental health innovations, such as telehealth, apps, messaging services, and any Internet-based mental health technology in clinical practice. Developed by the Mental Health Commission of Canada in partnership with the Centre for Research in Family Health, IWK Health Centre, and in consultation with stakeholders

Other Mental Health Commission of Canada e-mental health resources can be found here.

Internet-Delivered Cognitive Behavioural Therapy for Major Depression and Anxiety Disorders - Evidence Highlights - Optimal Use - PUBLISHED: July 22, 2019