Major depressive disorder (MDD) is the occurrence of one or more major depressive episodes that last at least two weeks. Anxiety disorders include a range of conditions, including generalized anxiety disorder, panic disorder, and social anxiety disorder. MDD and anxiety disorders may be treated with pharmacological and/or psychological interventions such as cognitive behavioural therapy (CBT). CBT delivered via the Internet (iCBT) may mitigate barriers to accessing face-to-face CBT such as geographical distance or cost of treatment.
CADTH, in collaboration with Health Quality Ontario (HQO), completed an Optimal Use project on the use of iCBT in patients with mild to moderate MDD and anxiety. HQO completed a systematic review of the clinical and economic evidence, as well as an economic analysis, and direct patient engagement for patient preferences and values. CADTH developed reviews for patient perspectives and experiences (literature review), and ethical and implementation issues related to iCBT.