Islet Cell Transplantation for Patients with Unstable or Uncontrollable Diabetes Mellitus: Clinical Effectiveness, Cost-Effectiveness and Guidelines


( Last Updated : March 18, 2020)
Project Status:
Completed
Project Line:
Reference List
Project Sub Line:
Reference List
Project Number:
RA1093-000

Details


Question


  1. What is the clinical effectiveness of islet cell transplantation in patients with unstable diabetes mellitus?

  2. What is the cost-effectiveness of using islet cell transplantation in patients with unstable diabetes mellitus?

  3. What are the evidence-based guidelines associated with the use of islet cell transplantation in patients with unstable diabetes mellitus?


Key Message

Three health technology assessments, one randomized controlled trial, and three non-randomized studies were identified regarding the clinical effectiveness of islet cell transplantation in patients with unstable diabetes mellitus. In addition, one economic evaluation was identified regarding the cost-effectiveness of using islet cell transplantation in patients with unstable diabetes mellitus. Lastly, one evidence-based guideline associated with the use of islet cell transplantation in patients with unstable diabetes mellitus was identified.