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Major Depressive Disorder – Focused Critical Appraisal of a Network Meta-Analysis

Last updated: February 18, 2020
Project Number: HE0022-000
Product Line: Technology Review
Research Type: Drug
Result type: Report

Major depressive disorder (MDD) is a common, debilitating, and recurrent mental health disorder. Over the past decades, multiple classes of antidepressant drugs have been developed to treat this condition. The relative effectiveness and safety of antidepressants are uncertain. This project will review a recently published network meta-analysis featuring broad comparisons of several oral antidepressants for MDD. Implications for decision-making will be discussed.