Major Depressive Disorder – Focused Critical Appraisal of a Network Meta-Analysis


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Project Line:
Health Technology Review
Project Sub Line:
Technology Review
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Major depressive disorder (MDD) is a common, debilitating, and recurrent mental health disorder. Over the past decades, multiple classes of antidepressant drugs have been developed to treat this condition. The relative effectiveness and safety of antidepressants are uncertain. This project will review a recently published network meta-analysis featuring broad comparisons of several oral antidepressants for MDD. Implications for decision-making will be discussed.