CADTH | Evidence Driven
CADTH | Evidence Driven

Methadol Liquid, Methadone, and Compounded Methadone in Patients with Opioid-Use Disorder Using Opioid Agonist Therapy: Comparative Clinical Effectiveness and Guidelines – An Update

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Project Status:
Completed
Project Line:
Reference List
Project Sub Line:
Reference List
Project Number:
RA1076-000

Question

  1. What is the comparative clinical effectiveness of compounded methadone versus methadol liquid or methadone in patients with opioid use disorder or withdrawal using opioid agonist therapy?
  2. What are the evidence-based guidelines on the use of compounded methadone versus methadol liquid or methadone in patients with opioid use disorder or withdrawal using opioid agonist therapy?

Key Message

No relevant literature was identified regarding the clinical effectiveness of compounded methadone versus methadol liquid or methadone in patients with opioid use disorder or withdrawal using opioid agonist therapy. In addition, no relevant evidence-based guidelines were identified regarding the use of clinical compounded methadone versus methadol liquid or methadone in patients with opioid use disorder or withdrawal using opioid agonist therapy.

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Methadol Liquid, Methadone, and Compounded Methadone in Patients with Opioid-Use Disorder Using Opioid Agonist Therapy: Comparative Clinical Effectiveness and Guidelines – An Update Rapid Response December 16, 2019 View PDF

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Last Updated : December 16, 2019