Monitoring for Drug-Induced Anaphylaxis with Injectable Antibiotics

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Project Status:
Completed
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Summary of Abstracts
Project Number:
RB1674-000

Question

  1. What is the clinical evidence describing risk of drug-induced anaphylaxis with a first dose of injectable antibiotics administered intravenously versus intramuscularly?
  2. What is the clinical evidence describing monitoring for drug-induced anaphylaxis with a first dose of antibiotics in a nonacute health care setting?
  3. What are the evidence-based recommendations concerning monitoring for drug-induced anaphylaxis for a first dose of antibiotics?

Key Message

We did not find any studies describing the risk of drug-induced anaphylaxis with a first dose of injectable antibiotics administered intravenously versus intramuscularly. We did not find any studies describing monitoring for drug-induced anaphylaxis with a first dose of antibiotics in a nonacute health care setting. We did not find any evidence-based recommendations concerning monitoring for drug-induced anaphylaxis for a first dose of antibiotics. We identified other references on this topic that may be of interest, which are listed in the report.