Key Message
Two systematic reviews were included in this report, however no evidence regarding the clinical utility of different frequencies of multidisciplinary medication review was identified. No evidence for the cost-effectiveness of multidisciplinary medication review every three months among patients in long-term care settings, and no guidelines on multidisciplinary medication reviews, were identified. This report was limited by the lack of primary evidence. Further research on multidisciplinary medication reviews may help to reduce uncertainty in their clinical utility and cost-effectiveness.