Platelet-Rich Plasma Injections for Chronic Tendinopathies in the Lower Extremities

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Project Status:
Completed
Project Line:
Health Technology Review
Project Sub Line:
Rapid Review
Project Number:
RC1486-000
Effective finish date:

Question

  1. What is the clinical effectiveness of platelet-rich plasma injections (PRPis) for the treatment of adults with chronic tendinopathies in the lower extremities?

Key Message

Findings from systematic reviews describing comparative clinical evidence for platelet-rich plasma injections (PRPis) in the treatment of chronic tendinopathies of the lower extremities were mixed. The systematic reviews we identified were often unclear concerning the components or treatment protocols used in the administration of PRPi, which may have contributed to the lack of a clear demonstration of effect. The variety of patient populations, comparisons, and outcomes in the included systematic reviews may also have contributed to the mixed findings. The lack of a clear demonstration of the comparative clinical effectiveness of PRPi in chronic tendinopathies of the lower extremities does not currently support decision-making in favour of its use.