Prevention of Tuberculosis: A Review of Guidelines


Project Status:
Project Line:
Health Technology Review
Project Sub Line:
Summary with Critical Appraisal
Project Number:


  1. What are the evidence-based guidelines for the prevention of tuberculosis infection?

Key Message

Nine evidence-based guidelines for the prevention of tuberculosis (TB) infection were identified and included in this report.Five guidelines include recommendations regarding the use of the Bacillus Calmette-Guérin (BCG) vaccine for the prevention of TB. Six guidelines include recommendations regarding risk reduction measures to reduce the risk of TB transmission. Overall, there are three high-quality, one moderate-quality, and five low-quality guidelines that include between one and 71 recommendations on the prevention of TB. The recommendations vary in strength and the quality of the evidence. The population and setting of interest may determine which guideline(s) and which recommendation(s) are of interest.