Reimbursement Review Reports

The latest CADTH Reimbursement Review reports are posted to this page. CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class. The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec. Implementation advice and funding algorithms are provided where applicable.

Brand Name Generic Name Therapeutic Area Recommendation Type Project Status Sort descending Date Submission Received Date Recommendation Issued
Keytruda pembrolizumab Esophageal carcinoma, gastroesophageal junction adenocarcinoma Reimburse with clinical criteria and/or conditions Complete
Reblozyl luspatercept Myelodysplastic syndromes-associated anemia Reimburse with clinical criteria and/or conditions Complete
Tukysa tucatinib Advanced or Metastatic Breast Cancer Reimburse with clinical criteria and/or conditions Complete
Onureg azacitidine Acute myeloid leukemia Reimburse with clinical criteria and/or conditions Complete
Trikafta elexacaftor / tezacaftor / ivacaftor and ivacaftor Cystic fibrosis, F508del CFTR mutation Reimburse with clinical criteria and/or conditions Complete
Breztri Aerosphere budesonide/ glycopyrronium /formoterol fumarate chronic obstructive pulmonary disease (COPD) Reimburse with clinical criteria and/or conditions Complete
Vitrakvi larotrectinib Solid tumours with NTRK gene fusion Reimburse with clinical criteria and/or conditions Complete
Myalepta metreleptin Leptin deficiency in lipodystrophy Active
Adtralza tralokinumab atopic dermatitis (AD) Active
TBC sotatercept Pulmonary arterial hypertension (WHO group 1) Active