Reimbursement Review Reports

The latest CADTH Reimbursement Review reports are posted to this page. CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class. The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec. Implementation advice and funding algorithms are provided where applicable.

Brand Name Generic Name Therapeutic Area Recommendation Type Sort descending Project Status Date Submission Received Date Recommendation Issued
Firdapse amifampridine phosphate Lambert-Eaton Myasthenic Syndrome, adults Reimburse with clinical criteria and/or conditions Complete
Lenvima and Keytruda lenvatinib and pembrolizumab advanced or metastatic renal cell carcinoma Reimburse with clinical criteria and/or conditions Complete
Albrioza sodium phenylbutyrate and ursodoxicoltaurine Amyotrophic lateral sclerosis (ALS) Reimburse with clinical criteria and/or conditions Complete
Trikafta elexacaftor/tezacaftor/ivacaftor and ivacaftor Cystic fibrosis, F508del CFTR mutation, 6 years and older Reimburse with clinical criteria and/or conditions Complete
Palynziq pegvaliase Phenylketonuria Reimburse with clinical criteria and/or conditions Complete
Tecentriq atezolizumab Non-small cell lung cancer Reimburse with clinical criteria and/or conditions Complete
Rozlytrek entrectinib Extracranial solid tumours with NTRK gene fusion Reimburse with clinical criteria and/or conditions Complete
Vyndaqel tafamidis Transthyretin-mediated amyloidosis Reimburse with clinical criteria and/or conditions Complete
Vabysmo faricimab Macular degeneration, age-related Reimburse with clinical criteria and/or conditions Complete
Keytruda pembrolizumab Triple-negative breast cancer Reimburse with clinical criteria and/or conditions Complete