Reimbursement Review Reports

The latest CADTH Reimbursement Review reports are posted to this page. CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class. The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec. Implementation advice and funding algorithms are provided where applicable.

Brand Name Generic Name Therapeutic Area Recommendation Type Project Status Date Submission Received Sort descending Date Recommendation Issued
Orkambi lumacaftor/ivacaftor Cystic Fibrosis, F508del CFTR mutation in patients 6 years and older Do not reimburse Complete
Viberzi eluxadoline Irritable bowel syndrome with diarrhea Do not reimburse Complete
Lapelga Pegfilgrastim Febrile neutropenia N/A Complete
Fasenra benralizumab Asthma, severe eosinophilic Reimburse with clinical criteria and/or conditions Complete
Trelegy Ellipta fluticasone furoate umeclidinium vilanterol Chronic obstructive pulmonary disease (COPD) Reimburse with clinical criteria and/or conditions Complete
Gazyva Obinutuzumab Follicular Lymphoma (previously untreated) Do not reimburse Complete
Perjeta-Herceptin Combo Pack Pertuzumab-Trastuzumab Combo Pack Early Breast Cancer Do not reimburse Complete
Erleada Apalutamide non-metastatic castrate resistant prostate cancer (nm-CRPC) Reimburse with clinical criteria and/or conditions Complete
Nucynta tapentadol hydrochloride pain, severe Do not reimburse Complete
Opdivo in combination with Yervoy Nivolumab in combination with Ipilimumab Advanced or Metastatic Renal Cell Carcinoma (RCC). Reimburse with clinical criteria and/or conditions Complete