Last Updated : September 12, 2023
Details
FilesProject Status:
Completed
Project Line:
Health Technology Review
Project Sub Line:
Health Technology Assessment
Project Number:
HT0041-000
Several drug treatments for COVID-19 caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are approved for use in Canada. This systematic review evaluated the efficacy, effectiveness, and safety of remdesivir for the treatment of COVID-19 in nonhospitalized adult patients from settings within the health care systems in Canada or from countries with economies similar to Canada. We also characterized which nonhospitalized patients are most likely to benefit from treatment with remdesivir.
Findings from 1 randomized controlled trial and 9 comparative observational studies are limited because of small sample sizes, uncontrolled underlying factors that could distort the relationship between remdesivir and comparators, and conflicting results. Because of these limitations, firm conclusions cannot be made. Further evidence is needed.
Files
Last Updated : September 12, 2023