CADTH | Evidence Driven
CADTH | Evidence Driven

Rheumatoid Factor and Anti-cyclic Citrullinated Peptide Testing for Arthralgia: Diagnostic Accuracy, Clinical Utility, and Guidelines

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Project Status:
Completed
Project Line:
Reference List
Project Sub Line:
Summary of Abstracts
Project Number:
RB1529-000

Question

  1. What is the diagnostic accuracy of rheumatoid factor tests for patients presenting with arthralgia but no arthritis on a physical exam?
  2. What is the diagnostic accuracy of anti-cyclic citrullinated peptide tests for patients presenting with arthralgia but no arthritis on physical exam?
  3. What is the clinical utility of rheumatoid factor tests for patients presenting with arthralgia but no arthritis on physical exam?
  4. What is the clinical utility of anti-cyclic citrullinated peptide tests for patients presenting with arthralgia but no arthritis on physical exam?
  5. What are the evidence-based guidelines regarding rheumatoid factor tests or anti-cyclic citrullinated peptide tests for patients presenting with arthralgia but no arthritis on physical exam?

Key Message

One non-randomized study was identified regarding the diagnostic accuracy of rheumatoid factor tests and anti-cyclic citrullinated peptide tests for patients presenting with arthralgia but no arthritis on a physical exam. No relevant literature was identified regarding the clinical utility of rheumatoid factor tests or anti-cyclic citrullinated peptide tests for patients presenting with arthralgia but no arthritis on physical exam. No relevant evidence-based guidelines were identified regarding rheumatoid factor tests or anti-cyclic citrullinated peptide tests for patients presenting with arthralgia but no arthritis on physical exam.

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Rheumatoid Factor and Anti-cyclic Citrullinated Peptide Testing for Arthralgia: Diagnostic Accuracy, Clinical Utility, and Guidelines Rapid Response November 16, 2020 View PDF

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Last Updated : November 26, 2020