Route of Administration of Sufentanil and Fentanyl for Patients in Palliative Care

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Project Status:
Completed
Project Line:
Reference List
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Reference List
Project Number:
RA1245-000
Effective finish date:

Question

  1. What is the clinical effectiveness of administering synthetic opioids (i.e., fentanyl, sufentanil) subcutaneously versus sublingually or intranasally for patients in palliative care?
  2. What is the clinical effectiveness of administering synthetic opioids (i.e., fentanyl, sufentanil) sublingually versus intranasally for patients in palliative care?
  3. What are the evidence-based guidelines regarding the route of administration for synthetic opioids (i.e., fentanyl, sufentanil) for patients in palliative care?

Key Message

We did not find any studies about the clinical effectiveness of administering synthetic opioids (i.e., fentanyl, sufentanil) subcutaneously versus sublingually or intranasally for patients in palliative care.

We found 2 non-randomized studies about the clinical effectiveness of administering synthetic opioids (i.e., fentanyl, sufentanil) sublingually versus intranasally for patients in palliative care.

We did not find any evidence-based guidelines about the route of administration for synthetic opioids (i.e., fentanyl, sufentanil) for patients in palliative care.