Tetrasodium Ethylenediaminetetraacetic Acid for Locking Central Venous Access Devices: Clinical Effectiveness, Cost-Effectiveness, and Guidelines

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RB1324-000

Question

  1. What is the clinical effectiveness of 4% tetrasodium ethylenediaminetetraacetic acid (EDTA) for locking central venous access devices (CVAD)?
  2. What is the cost-effectiveness of 4% tetrasodium EDTA for locking CVADs?
  3. What are the evidence-based guidelines regarding the use of CVADs?

Key Message

One randomized controlled trial was identified regarding 4% tetrasodium ethylenediaminetetraacetic acid (EDTA) for locking central venous access devices (CVADs). In addition, one evidence-based guideline was identified regarding the use of CVADs. No relevant economic evaluations were identified regarding the cost-effectiveness of 4% tetrasodium EDTA for locking CVADs.