Therapeutic Substitution of Drug Treatment for Multi-Drug Resistant Tuberculosis: Guidelines

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Project Status:
Completed
Project Line:
Reference List
Project Sub Line:
Summary of Abstracts
Project Number:
RB1501-000

Question

  1. What are the evidence-based guidelines regarding the therapeutic substitution of different drugs for the treatment of multi-drug resistant tuberculosis when there is a shortage of, or limited access to, the first line treatment?
  2. What are the evidence-based guidelines regarding the therapeutic substitution of different drugs for the treatment of multi-drug resistant tuberculosis when there is an intolerance to the first line treatment?

Key Message

Three evidence-based guidelines were identified regarding the therapeutic substitution of different drugs for the treatment of multi-drug resistant tuberculosis when there is a shortage or intolerance of the first line treatment.