Therapeutic Substitution of Drugs for the Treatment of Tuberculosis: Guidelines


( Last Updated : June 29, 2020)
Project Line:
Reference List
Project Sub Line:
Summary of Abstracts
Project Number:
RB1500-000

Details


Question


  1. What are the evidence-based guidelines regarding the therapeutic substitution of different drugs for the treatment of tuberculosis when there is a shortage of, or limited access to, the first line treatment?

  2. What are the evidence-based guidelines regarding the therapeutic substitution of different drugs for the treatment of tuberculosis when there is an intolerance of the first line treatment?

  3. What are the evidence-based guidelines regarding the therapeutic substitution of different drugs for the treatment of tuberculosis when there is resistance to one of the drugs in the first line treatment?


Key Message

Three evidence-based guidelines were identified regarding the therapeutic substitution of different drugs for the treatment of tuberculosis when there is resistance to one of the drugs in the first line treatment. No relevant evidence-based guidelines were identified regarding the therapeutic substitution of different drugs for the treatment of tuberculosis when there is a shortage or intolerance of the first line treatment