Eleven evidence-based guidelines for the treatment of tuberculosis (TB) were identified and included in this report. Four guidelines include recommendations regarding therapies for treating latent TB infection. Seven guidelines include recommendations regarding the treatment options for active TB disease. Nine guidelines include recommendations about different approaches for administering TB treatments. Overall, there were four high-quality and seven low-quality guidelines that include between one and 23 recommendations on the treatment of TB. The recommendations vary in strength and the quality of the evidence. The population and setting of interest may determine which guideline(s) and which recommendation(s) are of interest.