( Last Updated : December 10, 2020)
Generic Name:
Project Status:
Therapeutic Area:
Eosinophilic esophagitis, adults
AVIR Pharma Inc.
Call for patient/clinician input open:
Brand Name:
Project Line:
Reimbursement Review
Project Number:
Call for patient/clinician input closed:


Manufacturer Requested Reimbursement Criteria1:
For the induction of clinico-pathological remission in adults with eosinophilic esophagitis (EoE), as per Health Canada indication
Submission Type:
Fee Schedule:
Schedule A
Indicated for the induction of clinico-pathological remission in adults with eosinophilic esophagitis (EoE)
Recommendation Type:
Reimburse with clinical criteria and/or conditions
Final Recommendation:
  1. The requested reimbursement criteria are provided by the applicant and do not necessarily reflect the views of CADTH. Reimbursement criteria from CADTH will be documented in the final recommendation, if applicable.

Key Milestones2

Call for patient input postedSeptember 03, 2019
Patient group input closedOctober 23, 2019

- Patient input submission received from AEDESEO, American Partnership for Eosinophilic Disorders, ausEE Inc., CURED foundation, Gastrointestinal Society and FABED Families Affected by Eosinophilic Disorder

Patient input summary sent for review to patient input groupsDecember 04, 2019
Patient group comments on input summary closedDecember 11, 2019

- Patient input summary feedback received

Submission receivedNovember 08, 2019
Submission acceptedNovember 22, 2019
Review initiatedNovember 25, 2019

- Selected for CADTH/INESSS Joint Clinician Engagement

- Submission temporarily suspended pending receipt of information

- Additional information has been received and the temporary suspension of the review has been lifted

Draft CADTH review report(s) sent to sponsorMarch 24, 2020
Comments from sponsor on draft CADTH review report(s) receivedApril 02, 2020
CADTH review team's comments on draft CADTH review report(s) sent to sponsorMay 07, 2020
Canadian Drug Expert Committee (CDEC) meetingMay 20, 2020
CDEC recommendation sent to sponsor and drug plansJune 01, 2020
Embargo period endedJuly 14, 2020

- Request for extension to embargo period received from the sponsor

- Embargo extension request granted

- Reconsideration requested

Sponsor's request for reconsideration placed on CDEC agendaOctober 21, 2020
CDEC Final Recommendation & CADTH review report(s) issued to sponsor and drug plansOctober 28, 2020
CDEC Final Recommendation postedOctober 30, 2020
Redaction requests from sponsor on draft CADTH review report(s) receivedNovember 11, 2020
Final CADTH review report(s) postedDecember 09, 2020