Last Updated : March 6, 2023
Liquid biopsy is an emerging technology that detects genomic information in bodily fluids and could alter traditional pathways of care for cancer. While traditional approaches of precision-based testing rely on surgical biopsies, liquid biopsies could shift existing approaches toward less invasive testing technologies. The technology is based on growing evidence that among certain cancers, tumour cells can release DNA into bodily fluids. These DNA fragments may have a distinct genomic profile compared with DNA shed from healthy cells and, with the appropriate testing technology, can help describe features about the cancer that can be important for guiding treatment.
Although different types of liquid biopsy–based testing technologies exist, tests that are used to guide treatment decisions after a cancer diagnosis, rather than tests used for screening, were specifically selected as 1 of the top precision medicine technologies to watch over the next 5 years.
Examples of emerging technologies and their assessments include: