Key Message
Six systematic reviews (three with meta-analyses) and two randomized controlled trials were identified regarding the clinical effectiveness of orthotic bracing and splinting of the lower extremities in patients with chronic, non-cancer pain. Moreover, two non-randomized studies were identified regarding the clinical effectiveness of orthotic bracing and splinting of the spine in patients with chronic, non-cancer pain. Four evidence-based guidelines were identified regarding orthotic bracing or splinting of the lower extremities for chronic, non-cancer pain.