Transanal Total Mesorectal Excision for Adult Patients with Rectal Cancer

Details

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Project Status:
Completed
Project Line:
Health Technology Review
Project Sub Line:
Rapid Review
Project Number:
RC1459-000
Expected finish date:

Question

  1. What is the clinical effectiveness of transanal total mesorectal excision for adults with rectal cancer?
  2. What is the cost-effectiveness of transanal total mesorectal excision for adults with rectal cancer?

Key Message

Transanal total mesorectal excision may result in lower rates of conversion to open procedure and a better circumferential resection margin compared with laparoscopic total mesorectal excision in adults with rectal cancer.

Transanal total mesorectal excision may be comparable to laparoscopic total mesorectal excision for cancer recurrence, survival, death, and short-term safety outcomes in adults with rectal cancer.

Total mesorectal excision may be more cost-effective than laparoscopic and open total mesorectal excision in adults with rectal cancer, but this is uncertain.