Real-Time Continuous Glucose Monitoring for People Living With Type 1 Diabetes


( Last Updated : August 22, 2022)
Project Status:
Completed
Project Line:
Health Technology Review
Project Sub Line:
Rapid Review
Project Number:
RC1442-000

Details


Question

  1. What is the clinical effectiveness of monitoring glycemia with rtCGM for adults living with type 1 diabetes?
  2. What is the clinical effectiveness of monitoring glycemia with rtCGM for pediatric patients living with type 1 diabetes?
  3. What is the cost-effectiveness of monitoring glycemia with rtCGM for people living with type 1 diabetes?

Key Message

  • Continuous glucose monitoring (CGM) is a method of glucose testing in which a sensor is inserted into the skin and continuously monitors interstitial glucose concentrations. Real-time continuous glucose monitoring (rtCGM) systems automatically measure glucose and display a recent glucose value.
  • Evidence suggests that rtCGM may improve hemoglobin A1C and time in range in adults and pediatric patients with type 1 diabetes, but this is uncertain.
  • Limited evidence suggests that in people with type 1 diabetes, there is little to no difference between rtCGM and self-monitoring of blood glucose (SMBG) on quality of life, diabetic ketoacidosis, and severe adverse events.
  • Safety evidence suggests that rtCGM may decrease severe hypoglycemia in adults and pediatric patients with type 1 diabetes, but this is uncertain.
  • rtCGM may be more cost-effective in the long term than SMBG in adults with type 1 diabetes.